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Peer-reviewed veterinary case report

Ultra-structure of the oral cavity epithelial cells in white rat after experimental application of Naran S preparation.

Journal:
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina
Year:
2004
Authors:
Wołoszyn, Iwona et al.
Affiliation:
Department of Inorganic Chemistry
Species:
rodent

Abstract

The effectiveness of the natural drug--Naran S was studied in the therapy of the topical inflammation of the oral cavity mucous membrane. The experiment was conducted on male Wistar rats that were subjected to induction of inflammatory condition by injecting Freund adjuvant and rinsing oral cavity with the infusion of the drug for the period of 28 days. The analysis of the ultra structure of the epithelium cells was conducted with the use of transmission electron microscope. It was observed that under the influence of the drug, the epithelium undergoes renewal, the cells are joined with thick desmosomes, the nuclei have the proper areolas and the mitochondrium matrix is not oedematic.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16145957/