Peer-reviewed veterinary case report
Ultrasound and pathology of schwannoma tumor in a goldfish fin
By Sirri, Rubina et al.·Published in Veterinary clinical pathology·2015·Department of Veterinary Medical Sciences, Italy·View original on PubMed →
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Original publication title: Ultrasonographic and pathologic study of schwannoma in a Goldfish (Carassius auratus).
- Species:
- fish
Plain-English summary
A Goldfish developed a noticeable lump on its back near the fin, which turned out to be a type of tumor called schwannoma. The fish underwent several tests, including ultrasound, to examine the mass, which showed it was well-defined but had some irregularities. Further analysis revealed that the tumor was made up of abnormal cells that were infiltrating the surrounding muscle. Unfortunately, this case highlights a serious condition, and while the specific outcome isn't mentioned, it indicates a significant health concern for the fish.
People also search for: goldfish tumor symptoms · goldfish lump on back · schwannoma in fish treatment
Abstract
An adult Goldfish (Carassius auratus) developed an exophitic, multinodular, mass in the dorsal region involving the fin. The clinical and pathologic approach included ultrasonography, cytology, histopathology, immunohistochemistry, and ultrastructural evaluation. B-mode and color Doppler ultrasonographic findings showed an oval, well-defined mass with slightly inhomogeneous parenchymatous echotexture associated with an intense intralesional vascularization. Cytology and histology revealed neoplastic pleomorphic spindle cells arranged in a storiform pattern or in palisades typical of Antoni A pattern schwannoma. Moderate anisocytosis and anisokaryosis and occasional binucleation were also present. The neoplastic tissue deeply infiltrated the skeletal muscle of the dorsal region. Immunohistochemistry showed a diffuse cytoplasmic immunoreactivity of neoplastic cells to S100 protein and proliferating cell nuclear antigen (PCNA); glial fibrillary acidic protein was negative. The PCNA proliferation rate was 23.5% (calculated as the mean of 10 fields). Ultrastructurally, neoplastic cells were juxtaposed with parallel nuclei forming the typical palisade pattern and sharing cytoplasmic and nuclear features with human schwannoma. This is the first cytologic description supplied with echographic investigation of a malignant schwannoma in a fish species.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26356489/