Peer-reviewed veterinary case report
Understanding osteoarthritis pain through animal models.
- Journal:
- Clinical and experimental rheumatology
- Year:
- 2017
- Authors:
- O'Brien, Melissa et al.
- Affiliation:
- Dalhousie University · Canada
Abstract
Osteoarthritis (OA) is the most prevalent musculoskeletal disease worldwide. Chronic pain remains the foremost concern of OA patients and is poorly controlled by available pharmacotherapies. Current preclinical research, which aims to develop analgesics better suited for OA, is largely dependent on animal models and laboratory pain testing. This review summarises commonly used small animal models for studying experimental OA, including their benefits and limitations. Also discussed are a variety of validated methods for studying pain within these models.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28967367/