Peer-reviewed veterinary case report
Cloudy left eye and eye inflammation in a dog with skin mast cell
By Boostrom, Brendan O et al.·Published in Veterinary ophthalmology·2014·William R. Pritchard Veterinary Medical Teaching Hospital, United States·View original on PubMed →
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Original publication title: Unilateral intraocular mastocytosis and anterior uveitis in a dog with subcutaneous mast cell tumors.
- Species:
- dog
Plain-English summary
A 9-year-old male Scottish terrier was brought in because his left eye became cloudy for about a week. He had a history of subcutaneous mast cell tumors, which are a type of skin cancer, and was receiving radiation therapy for one of them. After examining his eye, the vet found abnormal mast cells, indicating that the cancer had spread to the eye, a condition called intraocular mastocytosis. Unfortunately, the dog passed away seven months after the initial diagnosis.
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Abstract
A 9-year-old male castrated Scottish terrier was referred to the Radiation Oncology Service at the William R. Pritchard Veterinary Medical Teaching Hospital for palliative radiation therapy of an incompletely excised, recurrent subcutaneous mast cell tumor (MCT) located over the right scapula, and surgical removal of a perianal MCT. Three weeks after initial presentation and prior to the fifth radiation treatment, the patient was presented with cloudiness of the left eye of 3-7 days duration. Ophthalmic consultation revealed 3+ aqueous flare with a dependent, swirling component filling approximately one-third of the anterior chamber. Aqueocentesis was performed under general anesthesia. Cytology revealed mast cells with highly atypical morphology and considered most consistent with neoplasia. The patient died 7 months after pathologic diagnosis of MCT on the right shoulder and 2 months after the cytologic diagnosis of malignant mast cells in the left anterior chamber. To the authors' knowledge, this is the first report of intraocular involvement in a mammal with MCTs, described here as intraocular mastocytosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23578200/