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Peer-reviewed veterinary case report

Dog with severe kidney infection and encapsulated abscess in one

By Owaku, Kenta et al.·Published in The Journal of veterinary medical science·2025·Tokyo University of Agriculture and Technology, Japan·View original on PubMed

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Original publication title: Unilateral pyelonephritis with encapsulated structure in a dog.

Species:
dog
Drinking & peeingDogs

Plain-English summary

A young female Golden Retriever with a liver condition called a portosystemic shunt was brought in with low protein levels, high ammonia levels, and severe fluid buildup in her abdomen. Unfortunately, she did not survive. A thorough examination after her passing revealed serious kidney damage and an infection caused by a type of bacteria known as Staphylococcus pseudintermedius. This case highlights a rare and severe kidney infection that can occur in dogs, particularly those with underlying health issues.

People also search for: dog kidney infection symptoms · Golden Retriever ascites treatment · Staphylococcus infection in dogs

Abstract

A young female Golden Retriever with a portosystemic shunt presented with hypoalbuminemia, hyperammonemia, and severe ascites, ultimately succumbing to the illness. Necropsy revealed renal papillary necrosis in the right renal pelvis. Histological examination identified an encapsulated structure within the renal pelvis containing basophilic granules surrounded by an eosinophilic, multilayered capsule. Mass spectrometry analysis of the encapsulated structure identified predominant Staphylococcus pseudintermedius-specific proteins. This finding was further confirmed by PCR and immunohistochemistry, establishing an infection caused by Staphylococcus spp. This is the first documented case of papillary necrosis with an encapsulated structure as a severe manifestation of pyelonephritis associated with S. pseudintermedius.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40301018/