Peer-reviewed veterinary case report
How vets use unlicensed GS-441524 to treat feline infectious
By Schlachet, A et al.·Published in Schweizer Archiv fur Tierheilkunde·2026·Department of Clinical Veterinary Science·View original on PubMed →
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Original publication title: Unlicensed antiviral treatment with GS-441524: How are clinicians approaching feline infectious peritonitis in primary care practices?
- Species:
- cat
Plain-English summary
A group of cats diagnosed with feline infectious peritonitis (FIP) showed symptoms like not eating, weight loss, and being unusually tired. They were treated with an antiviral medication called GS-441524 for at least 12 weeks. The treatment was effective, and many of the cats improved significantly, with a notable recovery in their appetite and energy levels. This study highlights how primary care veterinarians are using this unlicensed treatment to help cats with FIP.
People also search for: cat not eating · feline infectious peritonitis treatment · GS-441524 for cats · cat weight loss causes · lethargy in cats
Abstract
The global availability of GS-441524 for treating feline infectious peritonitis (FIP) has increased in recent years, yet little data is available about how primary care veterinarians diagnose the disease. This study aimed to evaluate the diagnostic approach to FIP in primary care practices and compare findings between effusive and non-effusive forms. Retrospective analysis was conducted using a dataset of 243 cats treated with unlicensed GS-441524 in Western Switzerland, obtained via a social media platform, all of which completed a minimum of 12-weeks treatment. Demographics were consistent with previous reports. Effusive and non-effusive FIP forms were equally represented. Most common presenting complaints included hyporexia/anorexia (70 %; 166/236), weight loss (63 %; 149/236), and lethargy (59 %; 140/236). Hyporexia/anorexia was more common in cats with effusive FIP (P.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41504664/