Unlicensed antiviral treatment with GS-441524: How are clinicians approaching feline infectious peritonitis in primary care practices?

Abstract

The global availability of GS-441524 for treating feline infectious peritonitis (FIP) has increased in recent years, yet little data is available about how primary care veterinarians diagnose the disease. This study aimed to evaluate the diagnostic approach to FIP in primary care practices and compare findings between effusive and non-effusive forms. Retrospective analysis was conducted using a dataset of 243 cats treated with unlicensed GS-441524 in Western Switzerland, obtained via a social media platform, all of which completed a minimum of 12-weeks treatment. Demographics were consistent with previous reports. Effusive and non-effusive FIP forms were equally represented. Most common presenting complaints included hyporexia/anorexia (70 %; 166/236), weight loss (63 %; 149/236), and lethargy (59 %; 140/236). Hyporexia/anorexia was more common in cats with effusive FIP (P.