Peer-reviewed veterinary case report
Lethargy and vomiting in 3-year-old Labrador with liver inflammation
By Ladak, Malika·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2020·Ontario Veterinary College, Canada·View original on PubMed →
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Original publication title: Unusual case of pyogranulomatous hepatitis of suspected infectious etiology in a 3-year-old Labrador retriever dog.
- Species:
- dog
Plain-English summary
A 3-year-old spayed female Labrador retriever was brought to the vet because she was very tired, vomiting, not eating much, and having trouble breathing. After some tests, including a liver biopsy, the vet found signs of liver inflammation likely caused by an infection, but they couldn't pinpoint the exact cause. Tests for leptospirosis, a type of bacterial infection, came back negative, so while it might have contributed to her condition, the exact infection remains unknown. The dog received treatment for her symptoms, but further investigation would be needed to determine the best course of action.
People also search for: dog vomiting and lethargy · Labrador retriever liver disease · dog respiratory problems treatment
Abstract
A 3-year-old spayed female Labrador retriever dog was presented with clinical signs of lethargy, vomiting, hyporexia, and increased respiratory effort. An exploratory laparotomy was conducted and a liver biopsy submitted for histopathologic evaluation revealed moderate multifocal coalescing pyogranulomatous hepatitis. Clinical signs, hematological parameters, and liver histopathology suggested an infectious etiology, such as leptospirosis, mycobacteriosis, or fungal infection. Polymerase chain reaction (PCR) and immunohistochemistry (IHC) for leptospirosis were negative. The infectious etiology was not identified, but leptospirosis may have played a role in the disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32355355/