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Peer-reviewed veterinary case report

Canine nasal fungal infection signs and new treatments

By Peeters, Dominique & Clercx, CécileĀ·Published in The Veterinary clinics of North America. Small animal practiceĀ·2007Ā·Department of Veterinary Clinical SciencesĀ·View original on PubMed →

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Original publication title: Update on canine sinonasal aspergillosis.

Species:
dog

Plain-English summary

A young to middle-aged dog with nasal discharge may be suffering from sinonasal aspergillosis, a fungal infection in the nose. This condition is often linked to a local immune issue and can be diagnosed by seeing the fungal plaques during an endoscopy or through lab tests. Treatment can be tricky, but using topical antifungal medications like enilconazole or clotrimazole has shown to be effective, leading to better outcomes and shorter hospital stays for affected dogs.

People also search for: dog nasal discharge treatment Ā· sinonasal aspergillosis in dogs Ā· antifungal treatment for dogs

Abstract

Sinonasal aspergillosis is a frequent cause of nasal discharge that occurs in otherwise healthy, young to middle-aged dogs. A local immune dysfunction is suspected in affected animals, and the role of increased interleukin-10 mRNA expression in the nasal mucosa of affected dogs is currently under investigation. Despite recent advances in imaging techniques, the "gold standard" for diagnosing the disease is direct visualization of fungal plaques during endoscopy or observation of fungal elements on cytology or histopathologic examination. Treatment can be challenging; however, the use of topical enilconazole or clotrimazole through noninvasive techniques has increased the success of treatment and decreased the morbidity and duration of hospitalization.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17693205/