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Peer-reviewed veterinary case report

Update on Mineral and Bone Disorders in Chronic Kidney Disease.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2016
Authors:
Foster, Jonathan D
Affiliation:
Department of Clinical Studies · United States

Abstract

The inappropriate phosphorus retention observed in chronic kidney disease is central to the pathophysiology of mineral and bone disorders observed in these patients. Subsequent derangements in serum fibroblast growth factor 23, parathyroid hormone, and calcitriol concentrations play contributory roles. Therapeutic intervention involves dietary phosphorus restriction and intestinal phosphate binders in order to correct phosphorus retention and maintain normocalcemia. Additional therapies may be considered to normalize serum fibroblast growth factor 23 and parathyroid hormone.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/27436330/