Peer-reviewed veterinary case report
How long iodine stays in cat urine after contrast scan
By Allegrini, Gabriella et al.·Published in Journal of veterinary internal medicine·2024·Ontario Veterinary College, Canada·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Urinary iodine clearance after iodinated contrast administration to healthy cats.
- Species:
- cat
Plain-English summary
Ten healthy male cats were given an injection of a contrast dye containing iodine for a medical imaging procedure. After the injection, their urine showed a significant increase in iodine levels, peaking on the first day and returning to normal levels by the end of the second week. This means that if your cat has hyperthyroidism and needs treatment after receiving this type of contrast, it's best to wait at least two weeks before starting the iodine treatment.
People also search for: cat hyperthyroidism treatment after contrast · iodine clearance in cats · cat urine iodine levels after CT scan
Abstract
BACKGROUND: Exogenous iodine interferes with the uptake of radioactive iodine (I) by the thyroid gland. This has potential implications for the treatment of cats with hyperthyroidism that have recently undergone computed tomography (CT) with IV administration of iodinated contrast medium (ICM). HYPOTHESIS: To determine the time to normalize urinary iodine clearance after administration of ICM. We hypothesized that it would require 4 weeks for urinary iodine concentration (UIC) to decrease to baseline after IV administration of ICM. ANIMALS: Ten healthy adult neutered male cats. METHODS: All cats were sedated and received Iopamidol at a dose of 2 mL/kg (600 mg/kg). Urinary iodine and creatinine concentrations were measured before administration of Iopamidol and on days 1, 2, 3, 7, 10 and weeks 2 to 6 after administration. The urinary iodine-to-creatinine ratio (UICR) was calculated. Outcome variables were modeled using a linear mixed-effects model. RESULTS: Urinary iodine concentration increased 37- to 884-fold on Day 1 after ICM injection and returned to baseline during Week 2. Compared with baseline, UIC was significantly increased for Days 1 to 7 (all P < .001); UC was significantly lower for Days 1 to 10 (all P < .03); and UICR was significantly increased from Days 1 to 10 (all P < .001, except Day 10 P = .05). CONCLUSIONS: Urinary clearance of iodine after IV administration of ICM requires 10 days to return to baseline in healthy cats. A 2-week interval between the iodinated contrast study andI treatment could be appropriate but needs to be confirmed in hyperthyroid cats.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39231018/