Peer-reviewed veterinary case report
Urinary tract infections in cats with chronic kidney disease
By White, Joanna D et al.·Published in Journal of feline medicine and surgery·2013·Faculty of Veterinary Science, Australia·View original on PubMed →
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Original publication title: Urinary tract infections in cats with chronic kidney disease.
- Species:
- cat
Plain-English summary
A group of cats with chronic kidney disease (CKD) were tested for urinary tract infections (UTIs) to see how common they were and what signs might show up. Out of 25 cats, 18 had UTIs that didn't show obvious symptoms. The most common bacteria found was E. coli, and most responded well to a common antibiotic called amoxicillin-clavulanate. Interestingly, while older female cats were more likely to have these hidden infections, treating them didn't seem to affect how long the cats lived.
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Abstract
Routine urine cultures were performed in cats with chronic kidney disease (CKD) to assess the overall prevalence and clinical signs associated with a positive urine culture (PUC). An occult urinary tract infection (UTI) was defined as a PUC not associated with clinical signs of lower urinary tract disease or pyelonephritis. Multivariate logistic and Cox proportional hazard regression models were used to evaluate the risk factors for an occult UTI and its relationship with survival. There were 31 PUCs from 25 cats. Eighty-seven percent of PUCs had active urine sediments. The most common infectious agent was Escherichia coli and most bacteria were sensitive to amoxicillin-clavulanate. Eighteen of 25 cats had occult UTIs. Among cats with occult UTI, increasing age in female cats was significantly associated with PUC; no significant association between occult UTI and survival was found and serum creatinine was predictive of survival in the short term (200 days) only. In conclusion, among cats with CKD, those with occult UTI were more likely to be older and female, but there was no association with severity of azotaemia. The presence of an occult UTI, when treated, did not influence survival.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23232285/