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Peer-reviewed veterinary case report

Use and control of biotechnological methods.

Journal:
Revue scientifique et technique (International Office of Epizootics)
Year:
1990
Authors:
Thiel, H J & Pfaff, E
Affiliation:
Federal Research Centre for Virus Diseases of Animals · Germany

Plain-English summary

This research discusses how scientists use advanced techniques in molecular biology, particularly gene technology, to study viruses. They focus on methods that help identify viruses through processes like molecular cloning and sequencing their genetic material. These techniques also help create new tools for diagnosing infections and developing vaccines. The study looks at genetically modified live viruses to understand any potential risks associated with vaccines made from them. Overall, the research aims to improve our understanding of viruses and enhance vaccine safety.

Abstract

The use of molecular virology is described. Emphasis is placed on molecular biology, especially methods involving gene technology. The respective techniques allow characterisation of viruses by molecular cloning and nucleotide sequencing as well as the development of new diagnostic tools and vaccines. Genetically engineered live viruses serve as examples to study potential risks of vaccines derived from such viruses.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/1966726/