Peer-reviewed veterinary case report
Use of 111In-labeled autologous leukocytes to image an abdominal abscess in a horse.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1985
- Authors:
- Koblik, P D et al.
- Species:
- horse
Plain-English summary
In this study, researchers used a special imaging technique involving indium 111-labeled white blood cells to locate an abdominal abscess in a horse that had a noticeable lump in its belly and a past infection with Streptococcus equi. They found a specific area of radioactivity that matched the location of the abscess, with the best images appearing 48 hours after the injection. When they tested two healthy horses, there was no sign of radioactivity in the same area, indicating that the imaging was specific to the horse with the abscess. Although there were some damaged white blood cells from the procedure, there were no negative side effects, and the radiation levels were safe. Overall, the imaging technique was effective in identifying the abscess.
Abstract
Indium 111-labeled autologous leukocytes were used to image an abdominal abscess in a horse with a palpable abdominal mass and history of Streptococcus equi infection. A focal area of radioactivity was identified in the location corresponding to the abscess. Imaging of this focal uptake was optimal 48 hours after injection. Similar scans obtained in 2 clinically normal horses revealed no evidence of focal radioactivity in this region. The cell labeling procedure gave acceptable labeling efficiency (87.5%) but an excessive number of damaged WBC, resulting in persistent lung radioactivity on all images. No adverse effects were noted. Radiation measured in the horse and its excreta were well within acceptable limits.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/4019296/