Peer-reviewed veterinary case report
Miniature horse treated for ovarian bleeding with bovine hemoglobin
By Maxson, A D et al.·Published in Journal of the American Veterinary Medical Association·1993·Department of Clinical Studies, United States·View original on PubMed →
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Original publication title: Use of a bovine hemoglobin preparation in the treatment of cyclic ovarian hemorrhage in a miniature horse.
- Species:
- horse
Plain-English summary
A 4-year-old miniature horse mare was brought in for severe anemia caused by bleeding from her ovaries. After two blood transfusions caused serious reactions, the veterinarian used a blood substitute made from bovine hemoglobin instead. Thankfully, the mare did not have any adverse reactions to this treatment and made a full recovery. While more research is needed to confirm the safety of this blood substitute in horses, it showed promise as an alternative when traditional blood transfusions aren't an option.
People also search for: miniature horse anemia treatment · ovarian hemorrhage in horses · blood transfusion reactions in horses
Abstract
Anemia that was secondary to ovarian hemorrhage in a 4-year-old miniature horse mare was treated prior to laparotomy with polymerized ultrapurified bovine hemoglobin (PUBH). Two previous whole-blood transfusions had resulted in acute transfusion reaction, and a suitable blood donor could not be found among 9 horses, necessitating use of the blood substitute. Subsequent blood typing revealed the mare to be Aa-negative, with allo-antibodies against Aa in serum. Serious adverse reactions were not observed after infusion of PUBH, and the mare recovered. Although the safety and efficacy of using PUBH in horses has not been established, PUBH may prove to be an excellent alternative to whole-blood transfusions, when indicated.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8253625/