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Peer-reviewed veterinary case report

Treating canine Babesia gibsoni infection

By Lin, Ming-Yu & Huang, Hui-Pi·Published in Acta veterinaria Scandinavica·2010·National Taiwan University Veterinary Hospital·View original on PubMed

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Original publication title: Use of a doxycycline-enrofloxacin-metronidazole combination with/without diminazene diaceturate to treat naturally occurring canine babesiosis caused by Babesia gibsoni.

Species:
dog

Plain-English summary

A dog in Taiwan was diagnosed with babesiosis, a serious tick-borne disease caused by the parasite Babesia gibsoni, which can lead to anemia and other health issues. The dog was treated with a combination of three antibiotics: doxycycline, enrofloxacin, and metronidazole, sometimes along with an injection of diminazene diaceturate. The treatment was effective, with about 85% of dogs recovering within an average of 24 days, regardless of whether the injection was used. This suggests that the antibiotic combination alone is quite effective for treating this condition.

People also search for: dog babesiosis treatment · Babesia gibsoni symptoms · doxycycline for dogs · tick-borne disease in dogs

Abstract

Canine babesiosis is an important worldwide, tick-borne disease caused by hemoprotozoan parasites of the genus Babesia. Babesia gibsoni is the predominant species that causes canine babesiosis in Taipei, Taiwan. It is a small pleomorphic intraerythrocytic parasite that can cause erythrocyte destruction and hemolytic anemia. Efficacy of oral administration of a doxycycline-enrofloxacin-metronidazole combination with and without injections of diminazene diaceturate in the management of naturally occurring canine babesiosis caused by B. gibsoni was evaluated retrospectively. The overall efficacy of this combination of doxycycline-enrofloxacin-metronidazole in conjunction with and without administration of diminazene diaceturate was 85.7% and 83.3%, respectively; with a mean recovery time of 24.2 and 23.5 days, respectively. Concomitant use of intramuscular diminazene diaceturate may not improve the efficacy of a doxycycline-enrofloxacin-metronidazole combination in management of canine babesiosis caused by B. gibsoni.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20416095/