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Peer-reviewed veterinary case report

Use of a gold compound for the treatment of pemphigus foliaceus in a foal.

Journal:
Journal of the American Veterinary Medical Association
Year:
1982
Authors:
Power, H T et al.
Species:
horse

Plain-English summary

A 4-month-old foal was brought in for a skin problem that caused widespread scaling, crusting, and fluid oozing. The vet diagnosed the foal with pemphigus foliaceus, an autoimmune skin condition, after examining skin samples. The treatment involved a gold compound given weekly for 14 weeks, along with high doses of steroids for the first 5 weeks. After 12 weeks of treatment, the foal's skin condition completely cleared up.

Abstract

A 4-month-old foal was examined because of generalized exfoliative dermatitis, with thick scales, extensive crusting, and oozing of serum. A diagnosis of pemphigus foliaceus was made by histologic and immunopathologic examinations of skin biopsy specimens. The foal was treated with a gold compound, aurothioglucose (1 mg/kg once weekly for 14 weeks). For the initial 5 weeks, high-dose glucocorticoid treatments also was used. The skin disorder resolved entirely after 12 weeks of treatment.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/6800993/