Peer-reviewed veterinary case report
Use of a monoclonal antibody against Babesia bovis merozoite surface antigen-2c for the development of a competitive ELISA test.
- Journal:
- Annals of the New York Academy of Sciences
- Year:
- 2004
- Authors:
- Dominguez, Mariana et al.
- Affiliation:
- Instituto Nacional de Tecnologí
Abstract
Bovine babesiosis caused by Babesia bovis is a disease that hampers the production of beef and dairy cattle in tropical and subtropical regions of the world. New diagnostic methods based on recombinant antigens constitute valuable biotechnological tools for the strategic control of this disease. We have developed a competitive enzyme-linked immunosorbent assay that includes a recombinant form of the merozoite surface antigen-2c and a novel monoclonal antibody against it. Preliminary results showed that this test is able to identify specific antibodies against B. bovis from experimentally and naturally infected cattle.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15604488/