Peer-reviewed veterinary case report
Adult Mastiff dog died from heart inflammation caused by Neospora
By Meseck, Emily K et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2005·Department of Biomedical Sciences, United States·View original on PubMed →
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Original publication title: Use of a multiplex polymerase chain reaction to rapidly differentiate Neospora caninum from Toxoplasma gondii in an adult dog with necrotizing myocarditis and myocardial infarct.
- Species:
- dog
Plain-English summary
A 3-year-old male Mastiff unexpectedly died from severe heart inflammation and damage. Tests revealed that the cause was an infection from a protozoan called Neospora caninum, which affected his heart muscle. This case highlights that Neospora caninum can lead to serious heart problems in dogs, although it's not very common. Unfortunately, despite the identification of the infection, the dog did not survive.
People also search for: dog heart inflammation causes · Neospora caninum in dogs · Mastiff heart disease symptoms
Abstract
This report describes a 3-year-old male castrated Mastiff dog that died unexpectedly with locally extensive, acute, necrotizing myocarditis and myocardial infarction. Intralesional protozoal tachyzoites in the affected myocardium were confirmed to be Neospora caninum by a novel multiplex polymerase chain reaction (PCR) and immunohistochemistry. Protozoal organisms were not identified in other tissues by histology, immunohistochemistry, or PCR. The multiplex PCR assay was used to quickly provide preliminary results on fresh myocardium to differentiate N. caninum and Toxoplasma gondii. Neosporosis is an uncommon cause of myocarditis in adult dogs and differential diagnoses for myocarditis in this population of dogs are reviewed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16475515/