Peer-reviewed veterinary case report
Using a handheld beta-hydroxybutyrate sensor to detect ketones in dogs
By Henderson, Debra W & Schlesinger, Daniel P·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2010·The CARE Centre Animal Hospital, Canada·View original on PubMed →
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Original publication title: Use of a point-of-care beta-hydroxybutyrate sensor for detection of ketonemia in dogs.
- Species:
- dog
Plain-English summary
A study found that a new blood test device can help detect high levels of ketones in dogs, which can be a sign of serious health issues like diabetes. Traditional urine tests often miss the severity of the problem, especially in dehydrated dogs. The new point-of-care device was compared to standard lab tests and showed good results, although it sometimes gave slightly higher readings. This device could be a helpful tool for veterinarians to assess ketone levels more accurately in dogs.
People also search for: dog diabetes symptoms · how to test for ketones in dogs · dog blood test for ketones
Abstract
The urine test strip is the most common test used to detect ketones in veterinary patients, but it can underestimate the degree of ketonuria and hence, ketonemia. Additionally, adequate urine samples for analysis may be difficult to obtain from dehydrated animals. The standard method used to detect and monitor ketonemia in human medicine is measurement of serum or whole blood beta-hydroxybutyrate (βHOB). A point-of-care (POC) analyzer has been validated for this purpose in humans. This study compared the accuracy of the POC device to an enzymatic reaction laboratory method for measurement of βHOB in dogs. Although the POC sensor tended to overestimate βHOB concentrations, there was good correlation (R(2) = 0.96) and good agreement between the 2 methods with a bias +/- precision of 0.0860 +/- 0.3410 mmol/L βHOB. The POC βHOB sensor can be useful for assessing ketonemia in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21119867/