Peer-reviewed veterinary case report
Buprenorphine skin patch in cats shows no pain relief effect
By Murrell, J C et al.·Published in The Veterinary record·2007·Faculty of Veterinary Medicine, Netherlands·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Use of a transdermal matrix patch of buprenorphine in cats: preliminary pharmacokinetic and pharmacodynamic data.
- Species:
- cat
Plain-English summary
Six domestic shorthair cats, aged three to four years, were tested to see if a transdermal patch delivering buprenorphine, a pain medication, could help with pain relief. The patches were applied to their shaved skin and their response to heat was measured before and after the patch was put on. Unfortunately, the patches did not significantly improve the cats' pain response during the testing period, indicating that this method may not be effective for pain management in cats.
People also search for: cat pain relief patch · buprenorphine for cats · how to manage cat pain
Abstract
Six domestic shorthair cats, aged three to four years and weighing 5.1 to 7.4 kg, were used to assess the thermal antinociceptive effect of a transdermal buprenorphine patch, designed to supply 35 mug buprenorphine/hour, which was applied to the shaved thorax. The cats' thermal thresholds were tested before the patch was applied and two, four, six, eight, 10, 12, 14 and 16 hours after it had been applied, and then every six hours until it was removed after 72 hours, and for a further 24 hours afterwards. Blood was collected at each time to measure the plasma concentration of buprenorphine. The patches did not produce a significant change in the thermal thresholds of the cats throughout the testing period. The mean (sd) peak plasma buprenorphine concentration was 10 (0.81) ng/ml.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17468320/