Peer-reviewed veterinary case report
Activated carbon and dialysis to treat meloxicam overdose in a dog
By Covo, Mariel S et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2025·Department of Internal Medicine, United States·View original on PubMed →
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Original publication title: Use of Activated Carbon Hemoperfusion and Hemodialysis in the Treatment of a Meloxicam Overdose in a Dog.
- Species:
- dog
Plain-English summary
A 2-year-old neutered male Basset Hound mix was brought in after accidentally ingesting a high dose of meloxicam, a common pain medication. Although he showed no serious symptoms at first, blood tests indicated mild kidney issues. The veterinarians used a combination of activated carbon hemoperfusion and hemodialysis to remove the medication from his system, which significantly lowered the meloxicam levels in his blood. While he experienced some minor bleeding in his stool, he recovered well, and follow-up tests eight weeks later showed only slight kidney concerns.
People also search for: dog meloxicam overdose treatment · Basset Hound kidney issues · activated carbon hemoperfusion for dogs
Abstract
OBJECTIVE: To describe the use of activated carbon hemoperfusion (HP) and hemodialysis (HD) to treat a meloxicam overdose in a dog. CASE SUMMARY: A 2-year-old neutered male Basset Hound mix was presented for an accidental overdose of meloxicam of up to 5.5 mg/kg. The dog was asymptomatic on presentation with mild azotemia. In-series activated carbon HP and HD were performed. Fifteen blood volumes were processed over 207 min, resulting in an 87.5% decrease in the serum meloxicam concentration, with the greatest reduction occurring within the first hour of treatment. The dog developed self-limiting hematochezia but otherwise had no clinical concerns. Eight weeks after HP/HD treatment, follow-up bloodwork showed a relatively static, mild azotemia. NEW OR UNIQUE INFORMATION: This is the first clinical report to describe the successful use of activated carbon HP and HD in veterinary medicine and the first to document the use of HP to treat meloxicam toxicosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41313643/