Peer-reviewed veterinary case report
Treating pyometra in bitches with aglepristone and antibiotics
By Gürbulak, K et al.·Published in Acta veterinaria Hungarica·2005·Department of Obstetrics and Gynaecology·View original on PubMed →
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Original publication title: Use of aglepristone and aglepristone + intrauterine antibiotic for the treatment of pyometra in bitches.
Plain-English summary
A group of 24 female dogs aged 5 to 12 years was treated for pyometra, a serious infection of the uterus. Some dogs received a medication called aglepristone, while others received both aglepristone and antibiotics directly in the uterus. The dogs that received both treatments had a higher success rate, with 9 out of 11 responding well compared to 6 out of 13 with just aglepristone. This suggests that combining aglepristone with intrauterine antibiotics may be more effective for treating pyometra in dogs.
People also search for: dog pyometra treatment · aglepristone for dogs · dog uterus infection antibiotics
Abstract
In this study, the efficacy of aglepristone and/or intrauterine antibiotic administration for the treatment of bitches with cystic endometrial hyperplasia/pyometra complex was investigated. Twenty-four bitches (5-12 years old) with the diagnosis of pyometra were treated at the University of Kafkas and at Istanbul University. The diagnosis of pyometra was established on the basis of the results of clinical, ultrasonographic and vaginal examinations, the haematological and biochemical findings and the history data. In Group I (n = 13), aglepristone (Antiprogestin, Alizine, Virbac, France; 0.33 ml/kg, s.c.) was administered on days 1, 2, 7, and 14 (day 1: diagnosis). In Group II (n = 11), intrauterine antibiotic treatment was performed according to the antibiogram on days 1, 2, 4, 6, 8 in addition to aglepristone given as in Group I. Clinical and ultrasonographic examinations, haematological results and occurrence of oestrous cycles revealed that the ratio of effectively treated bitches was 6/13 and 9/11 in Groups I and II, respectively.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15959983/