Peer-reviewed veterinary case report
Amlodipine treatment for high blood pressure in cats in Japan
By Morita, Shohei et al.·Published in The Journal of veterinary medical science·2024·Tokyo University of Agriculture and Technology, Japan·View original on PubMed →
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Original publication title: Use of amlodipine in the treatment of cats with systemic hypertension in Japan.
- Species:
- cat
Plain-English summary
A group of cats in Japan with high blood pressure (hypertension) was treated with a medication called amlodipine. While this drug helped lower their blood pressure to normal levels, it was found that using it might negatively affect their survival. The study highlighted that many veterinary clinics in Japan do not routinely check blood pressure in cats, which could help catch hypertension early and improve treatment outcomes. Regular health checkups that include blood pressure measurements could be beneficial for identifying and managing this condition in cats.
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Abstract
An increase in systemic blood pressure causes bleeding and ischemia owing to peripheral vascular breakdown, leading to various forms of organ damage. The brain, eyes, kidneys, and cardiovascular system are known target organs for hypertension. To our knowledge, no reports in Japan describe, in detail, the types of antihypertensive drugs used to treat hypertension in cats or its underlying causes. Therefore, we aimed to investigate the use of antihypertensive drugs in domestic cats with hypertension in Japan, the causes of hypertension, and the vital prognosis of these patients. In the present survey, we found that amlodipine was used alone (60/80 cats) or concomitantly (20/80 cats) in all cat patients with hypertension in Japan. We also determined that blood pressure measurements were not yet routinely performed on cats at veterinary clinics in Japan. Furthermore, we have new information suggesting that amlodipine administration in cats with hypertension, which lowers systolic arterial pressure levels to within the normal range (<140 mmHg), may have a negative impact on their survival. Routine blood pressure measurements for cats during their regular health checkups can help identify hypertension, and proper interpretation of blood pressure readings can facilitate suitable treatment measures.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38569838/