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Peer-reviewed veterinary case report

Treating infected dog knee surgery wounds with antibiotic sponges

By Lee, Sylvia J et al.·Published in Veterinary surgery : VS·2019·Surgery Department, United States·View original on PubMed

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Original publication title: Use of an amikacin-infused collagen sponge concurrent with implant removal for treatment of tibial plateau leveling osteotomy surgical site infection in 31 cases.

Species:
dog

Plain-English summary

A group of 31 dogs that developed infections after a knee surgery called tibial plateau leveling osteotomy (TPLO) were treated with a special collagen sponge infused with an antibiotic called amikacin, along with the removal of the surgical implants. Most dogs healed well after the procedure, with 24 showing no issues and only a few experiencing minor inflammation that resolved on its own. After a follow-up period of nearly two years, there were no signs of infection returning, and the dogs did not show any lameness. This treatment approach proved to be highly effective for managing surgical site infections in these dogs.

People also search for: dog knee surgery infection treatment · TPLO surgery recovery · amikacin for dog infections

Abstract

OBJECTIVE: To report the use and long-term outcome of dogs with surgical site infection (SSI) after tibial plateau leveling osteotomy (TPO), treated with an amikacin-infused collagen sponge and implant removal. STUDY DESIGN: Retrospective study. ANIMALS: Thirty-one client-owned dogs. METHODS: Medical records were reviewed for dogs with SSI after a TPLO that were treated with surgical implant removal and concurrent implantation of an amikacin-infused collagen sponge. Relevant clinical and surgical data were recorded. The TPLO implants were routinely removed; the surgical site was swabbed for culture. The sponge was aseptically infused with amikacin prior to implantation. Postprocedure examinations consisted of visual inspection of the incision by the surgeon and lameness scoring. RESULTS: Thirty-one dogs met all inclusion criteria. Median follow-up time was 687 days. Short-term examination after implant removal and sponge implantation revealed uneventful incisional healing in 24 dogs. Six (19.4%) dogs exhibited inflamed incision sites a median of 4 days (range, 3-9) postoperatively that resolved without additional treatment. One (3.2%) dog required empirical antibiotic treatment 7 days postoperatively but was lost to long-term follow-up. Long-term follow-up examination revealed no clinical evidence of SSI recurrence and no lameness in the remaining 30 cases. CONCLUSION: Surgical implant removal and implantation of an absorbable collagen sponge infused with amikacin alone was an effective treatment for postoperative TPLO SSI. CLINICAL SIGNIFICANCE: This procedure had a 96.8% long-term resolution of SSI. It should be considered as a treatment option for TPLO SSI.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31168817/