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Peer-reviewed veterinary case report

Healing chronic dog corneal defects with serum or Vizoovet

By Dees, D Dustin & Keys, Deborah A·Published in Veterinary ophthalmology·2022·Eye Care for Animals, United States·View original on PubMed

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Original publication title: Use of autologous serum or Vizoovet to improve healing rates of spontaneous chronic corneal epithelial defects after diamond burr debridement in dogs.

Species:
dog

Plain-English summary

A group of 120 dogs with chronic corneal epithelial defects (SCCEDs) underwent a procedure to remove damaged tissue from their eyes. After the procedure, some dogs received standard eye drops, while others were treated with either their own serum or a natural eye drop called Vizoovet, which contains ingredients like propolis and aloe vera. The dogs treated with Vizoovet healed significantly faster than those who only received standard drops, while the serum treatment also showed some improvement. Overall, Vizoovet proved to be an effective option for speeding up healing in these cases.

People also search for: dog eye problems treatment · Vizoovet for dogs · chronic corneal epithelial defect healing time

Abstract

PURPOSE: To determine whether the use of autologous serum or Vizoovet® improved healing rates of spontaneous chronic corneal epithelial defects (SCCEDs) after diamond burr debridement (DBD) in dogs. STUDY DESIGN: Two parallel group randomized prospective study with a historical control group. MATERIALS AND METHODS: Canine patients having undergone DBD for treatment of SCCEDs were included. Data for the control group (ofloxacin only) were gathered from patient records. Patients were randomly assigned to treatment groups for post-procedural medical treatments of ofloxacin and autologous serum (group 1) or ofloxacin and Vizoovet®, an all-natural eyed drop containing propolis, aloe vera, and chamomile (group 2). Each dog was examined between 2 and 3 weeks until the cornea was fluorescein stain negative. Data points collected included age, sex, breed, type of medications used, retention of bandage contact lens (BCL), time to healing, and number of DBD performed. RESULTS: A total of 120 dogs, each contributing one eye to the study, underwent DBD for SCCEDs. Mean (± standard deviation) days until healed were 20.1 ± 11.1 days, 16.3 ± 4.5 days, and 16.0 ± 3.7 days for the control group, group 1, and group 2, respectively. There was a marginally significant difference in days until healed between groups (p = .0515). SCCEDs healed significantly faster in group 2 (p = .03) and marginally faster in group 1 (p = .06) compared with the control group. Days until healing between group 1 and 2 were not significantly different (p = .76). CONCLUSIONS: As compared to the control group, use of Vizoovet® as adjunctive medical treatment resulted in shorter corneal healing time after DBD.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34786805/