Peer-reviewed veterinary case report
Pygmy goat with pemphigus foliaceus treated with steroids
By Valdez, R A et al.·Published in Journal of the American Veterinary Medical Association·1995·Department of Veterinary Pathobiology, United States·View original on PubMed →
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Original publication title: Use of corticosteroids and aurothioglucose in a pygmy goat with pemphigus foliaceus.
- Species:
- goat
Plain-English summary
A 20-month-old female pygmy goat was brought in for severe skin problems, including hair loss and flaky skin, which had been ongoing for three months. The vet diagnosed her with pemphigus foliaceus, an autoimmune skin condition, using skin samples for testing. She was treated with prednisolone, a steroid that helped her improve within a week, and her condition remained stable with ongoing treatment. However, another treatment with aurothioglucose did not prevent the skin issues from returning after stopping the steroids.
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Abstract
Pemphigus foliaceus was diagnosed in a 20-month-old female pygmy goat. The goat had a 3-month history of chronic exfoliative dermatitis and was examined after developing alopecia and severe, asymmetric, diffuse flakes of dry, nonadherent skin scales. Pemphigus foliaceus was diagnosed on the basis of dermatohistologic findings and was confirmed by analysis of results of direct immunofluorescence testing of perilesional specimens obtained by use of a punch biopsy. The goat was successfully treated with prednisolone (immunosuppressive induction dosage; 1 mg/kg of body weight, IM, q 12 h). Remission was achieved in 1 week and was maintained by use of prednisolone (immunosuppressive maintenance dosage; 1 mg/kg, IM, q 48 h). Treatment with aurothioglucose (1 mg/kg, IM, q 7 d) that was initiated during administration of prednisolone and was continued after discontinuation of corticosteroid administration failed to prevent redevelopment of pemphigus foliaceus.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7657579/