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Peer-reviewed veterinary case report

Dog with septic belly infection treated with plasma and antibiotics

By Ropski, Meaghan K et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2017·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Use of cryopoor plasma for albumin replacement and continuous antimicrobial infusion for treatment of septic peritonitis in a dog.

Species:
dog

Plain-English summary

A 5-year-old Bernese Mountain Dog was brought in for lethargy six days after surgery to remove a foreign object from his intestines. He developed septic peritonitis, a serious infection in his abdomen, due to a surgical complication. The vet used a combination of treatments, including a special type of plasma to replace lost proteins and continuous antibiotics to fight the infection. After a second surgery to fix the issue, the dog received supportive care and was able to go home 15 days later. A follow-up a year later showed he was doing well.

People also search for: dog lethargy after surgery · septic peritonitis treatment in dogs · Bernese Mountain Dog recovery after surgery

Abstract

OBJECTIVE: To report the successful management of a dog with septic peritonitis and septic shock secondary to enterectomy dehiscence using novel techniques for identification of intestinal dehiscence and for septic shock treatment. CASE SUMMARY: A 5-year-old castrated male Bernese Mountain Dog presented for lethargy 6 days following enterotomy for foreign body obstruction. Septic peritonitis was identified due to dehiscence of the enterotomy site, and resection and anastomosis were performed using a gastrointestinal anastomosis and thoracoabdominal stapling device. Postoperatively the patient experienced severe hypotension, which responded to norepinephrine constant rate infusion (CRI) after failing to improve with fluid therapy or dopamine CRI. Further treatment included antimicrobial CRI and supportive care including careful fluid therapy. Due to low effective circulating volume paired with intersititial fluid overload and large volume abdominal effusion, fluid therapy consisted of a combination of human serum albumin, canine albumin, synthetic colloids, and isotonic crystalloids. Cryopoor plasma (CPP) was used as a source of canine albumin and intravascular volume. On Day 4, food dye was given through a nasogastric tube due to suspicion of dehiscence of the anastomosis site. Dehiscence was confirmed during abdominal exploratory, and a second resection and anastomosis was performed. Abdominal partial closure with vacuum-assisted closure device was performed. Supportive care was continued with CPP CRI and imipenem CRI. Planned relaparotomy to change the vacuum-assisted closure device was performed 48 hours later, with abdominal closure 96 hours after anastomosis. The patient was discharged on Day 15. Recheck 12 months later was normal. NEW OR UNIQUE INFORMATION PROVIDED: This case includes novel techniques such food dye via nasogastric tube to identify anastomosis dehiscence, use of CPP as a source of canine albumin, and antimicrobial CRI in a dog with septic peritonitis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28135411/