Peer-reviewed veterinary case report
Treating deep corneal wounds in dogs and cats with pig tissue grafts
By Barachetti, Laura et al.·Published in The Veterinary record·2020·Department of Veterinary Medicine, Italy·View original on PubMed →
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Original publication title: Use of four-layer porcine small intestinal submucosa alone as a scaffold for the treatment of deep corneal defects in dogs and cats: preliminary results.
Plain-English summary
A group of 10 dogs and 3 cats with serious eye problems, including deep corneal ulcers and perforations, underwent surgery using a special graft made from pig intestine (Vetrix BioSIS plus+). After an average follow-up of about 86 days, 12 out of 13 treated eyes were able to see again, with most showing only mild scarring. While some pets had minor complications that were treated with medication, one dog had a severe reaction and needed to have its eye removed. Overall, the graft proved to be a promising option for helping pets with deep corneal defects regain their vision.
People also search for: dog corneal ulcer treatment · cat eye surgery recovery · Vetrix BioSIS for pets
Abstract
BACKGROUND: To describe the efficacy of four-layer porcine small intestinal submucosa (Vetrix BioSIS plus+) as single scaffold for the treatment of deep corneal lesions in dogs and cats. METHODS: 10 dogs and 3 cats with deep or full thickness corneal defects were treated surgically with BioSIS plus graft. Corneal transparency scores and vision were evaluated. RESULTS: Lesions in dogs were four perforations, three descemetoceles, two limbal melanocytomas and one deep corneal ulcer. In cats, there were one limbal melanocytoma and two perforations. The average length of the follow-up was 86 days. In all, 12 out of 13 eyes treated were visual at last recheck (92.3 per cent). The scars were mild eight cases (66.7 per cent), but denser in four cases (33.4 per cent). Complication were partial collagenolysis in three cases (25 per cent), which resolved with medical therapy, mild corneal pigmentation in one case (8.4 per cent) and anterior synechia in one case (8.4 per cent). One case experienced severe collagenolysis and was enucleated 21 days postoperatively. CONCLUSIONS: Four-layer porcine SIS graft was successfully used for surgical treatment of deep corneal lesions in selected corneal diseases in a small series of dogs and cats, with good results in terms of mechanic support and corneal transparency.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31937546/