Peer-reviewed veterinary case report
Use of herpesvirus papio 2 as an alternative antigen in immunoblotting assay for B virus diagnosis.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2004
- Authors:
- Tanaka, Seiichi et al.
- Affiliation:
- Department of Life Science · Japan
Abstract
Herpesvirus papio 2 (HVP2), which infects baboons, is much more closely related genetically and antigenically to monkey B virus (BV) than to human herpes simplex virus 1(HSV1) and other related herpes viruses. The usefulness of HVP2 as an alternative test antigen in immunoblotting assays to detect BV-antibody in macaque monkey sera was assessed. Six HVP2 proteins reacted with BV-positive sera in immunoblotting. No specific bands could be detected with BV-negative sera. These results show the usefulness of HVP2 antigen as an alternative and safer antigen than authentic BV antigen in detecting BV antibody in immunoblotting.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15187363/