Peer-reviewed veterinary case report
Use of inactivated Escherichia coli enterotoxins to enhance respiratory mucosal adjuvanticity during vaccination in swine.
- Journal:
- Clinical and vaccine immunology : CVI
- Year:
- 2011
- Authors:
- Barrette, Roger W et al.
- Affiliation:
- Department of Animal Science · United States
Abstract
In order to augment responses to respiratory vaccines in swine, various adjuvants were intranasally coadministered with a foot-and-mouth disease virus (FMDV) antigen to pigs. Detoxified Escherichia coli enterotoxins LTK63 and LTR72 enhanced antigen-specific mucosal and systemic immunity, demonstrating their efficacy as adjuvants for nonreplicating antigens upon intranasal immunization in swine.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21918121/