Peer-reviewed veterinary case report
Use of iohexol as a gastrointestinal contrast agent in three dogs, five cats, and one bird.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1993
- Authors:
- Williams, J et al.
- Affiliation:
- Department of Veterinary Clinical Sciences · United States
Plain-English summary
In this study, veterinarians explored the use of iohexol, a special type of contrast agent, for imaging the stomach and intestines in dogs, cats, and a bird. Typically, barium sulfate is used for these procedures, but it can't be used if there's a chance of a hole in the intestines. Iohexol is a safer option because it doesn't cause as much dilution in the intestines, which helps in spotting any issues like blockages or perforations. The results showed that iohexol worked well for these imaging studies without causing any side effects. Overall, the use of iohexol provided clear images and was effective for the intended purpose.
Abstract
Barium sulfate suspension is routinely used as contrast medium for upper gastrointestinal procedures. It has been contraindicated for use in cases of suspected perforation. In such instances, water-soluble iodides are recommended for use. Most of the water-soluble iodides available for use in veterinary medicine at this time are hyperosmolar. This results in in transit dilution of the contrast column. The dilution of the contrast agent within the intestines may prevent visualization of a perforation, especially if the perforation is in the distal portion of the small intestine. Iohexol a nonionic water-soluble iodide of low osmolality, is currently used in veterinary medicine for myelography. We have used it as the contrast agent for upper gastrointestinal studies in cases of suspected obstruction or perforation, with good results, and no adverse effects have been associated with its use. Opacity of the contrast column was adequate, and segmentation or flocculation of the column was not apparent.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/8449807/