Peer-reviewed veterinary case report
Linezolid treatment for MRSP blood infection and spine disease
By Foster, Jonathan D et al.·Published in Journal of the American Animal Hospital Association·2014·Department of Medical Sciences·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Use of linezolid to treat MRSP bacteremia and discospondylitis in a dog.
- Species:
- dog
Plain-English summary
A 1.5-year-old male German Shepherd was brought to the vet because he had repeated episodes of fever and seemed very tired. Tests showed he had an infection in his spine (discospondylitis) and blood tests revealed a resistant bacteria called methicillin-resistant Staphylococcus pseudintermedius (MRSP). Since this bacteria was resistant to most antibiotics, the vet used a special antibiotic called linezolid, which worked effectively over 23 weeks. After treatment, the dog fully recovered from the infection and his symptoms improved.
People also search for: dog fever lethargy · German Shepherd discospondylitis treatment · MRSP infection in dogs · linezolid for dog infection
Abstract
A 1.5 yr old male German shepherd dog was evaluated for recurrent intermittent episodes of fever and lethargy. Clinicopathologic abnormalities were suggestive of a discospondylitis at the seventh and eighth thoracic vertebrae. Blood and urine cultures yielded growth of methicillin-resistant Staphylococcus pseudintermedius (MRSP) that was resistant to all commonly used antibiotics. Extralabel antibiotic susceptibility testing demonstrated susceptibility of both blood and urine isolates to linezolid. The prescribed dose was extrapolated from pharmacokinetic (PK) studies and the isolate's plasma minimum inhibitory concentration (MIC). Linezolid was administered for 23 wk and resulted in successful resolution of bacteremia, bacteriuria, and discospondylitis. When justified, linezolid should be considered to treat methicillin-resistant infections.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24216492/