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Peer-reviewed veterinary case report

Use of low molecular weight heparin in cats: 57 cases (1999-2003).

Journal:
Journal of the American Veterinary Medical Association
Year:
2004
Authors:
Smith, Caren E et al.
Affiliation:
Department of Clinical Sciences · United States
Species:
cat

Abstract

OBJECTIVE: To determine duration of administration, complications, and frequency of aortic thromboembolism associated with administration of low molecular weight heparin (dalteparin) in cats. DESIGN: Retrospective study. ANIMALS: 57 cats treated with dalteparin PROCEDURE: Data were recorded from the medical records of cats treated with dalteparin, and owners were contacted by telephone for information regarding ease of administration and possible adverse effects. RESULTS: Dalteparin was easily administered by owners. Median dose was 99 U/kg (45 U/lb) once or twice daily. Bleeding complications were infrequent. Of 43 cats with cardiomyopathy that received owner-administered dalteparin for a median follow-up time of 172 days, 8 cats developed documented or possible arterial thromboembolism. CONCLUSIONS AND CLINICAL RELEVANCE: Dalteparin was easily administered by owners and was well tolerated by cats. Whether dalteparin administration can reduce the frequency or severity of arterial thromboembolism is not yet known.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15521447/