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Peer-reviewed veterinary case report

Lufenuron treatment for fungal infections in dogs and cats

By Ben-Ziony, Y & Arzi, B·Published in Journal of the American Veterinary Medical Association·2000·Ben Ziony's Animal Hospitals Ltd·View original on PubMed

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Original publication title: Use of lufenuron for treating fungal infections of dogs and cats: 297 cases (1997-1999).

Species:
dog
Skin & coatDogs

Plain-English summary

A group of 156 dogs and 201 cats with skin fungal infections were treated with a medication called lufenuron. The dogs received a single oral dose, and most showed improvement, with skin lesions resolving in about 21 days. The cats also improved quickly, with their lesions clearing up in around 12 days after treatment. In contrast, untreated animals took about 90 days to heal. No side effects were noted from the treatment, making lufenuron a safe and effective option for these infections.

People also search for: dog skin fungal infection treatment · cat dermatophytosis medication · lufenuron for pets

Abstract

OBJECTIVE: To evaluate use of lufenuron for treating cutaneous fungal infections in dogs and cats. DESIGN: Retrospective study. ANIMALS: 156 dogs and 201 cats with dermatophytosis or superficial dermatomycoses. PROCEDURE: Medical records were reviewed for dogs and cats that had been treated for dermatophytosis or other fungal infections by administration of lufenuron and 18 dogs and 42 cats that were not treated and served as a control group. RESULTS: Dogs were treated once by oral administration of lufenuron tablets at doses ranging from 54.2 to 68.3 mg/kg (24.6 to 31.0 mg/lb) of body weight. Samples of skin, scrapings, and hair were obtained daily from 14 dogs with dermatophytosis; mean durations from time of treatment to time of negative fungal culture results and resolution of gross lesions were 14.5 and 20.75 days, respectively. In all treated dogs, gross lesions resolved within approximately 21 days. Cats were treated once by oral administration of lufenuron suspension in doses ranging from 51.2 to 266 mg/kg (23.3 to 120.9 mg/lb). Samples were obtained daily from 23 cats; mean durations from time of treatment to time of negative fungal culture results and resolution of gross lesions were 8.3 and 12 days, respectively. Time to resolution of lesions in most untreated control animals was approximately 90 days. Adverse effects of treatment were not detected. CONCLUSIONS AND CLINICAL RELEVANCE: Results of this study suggest that lufenuron provides an effective, convenient, and rapid method for treating fungal infections in dogs and cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11128542/