Peer-reviewed veterinary case report
Cat with large skin wounds treated with metyrapone for pituitary
By Daley, C A et al.·Published in Journal of the American Veterinary Medical Association·1993·Department of Small Animal Surgery and Medicine·View original on PubMed →
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Original publication title: Use of metyrapone to treat pituitary-dependent hyperadrenocorticism in a cat with large cutaneous wounds.
- Species:
- cat
Plain-English summary
A cat with large skin wounds and thinning fur was diagnosed with pituitary-dependent hyperadrenocorticism, a condition that causes excessive cortisol production. The veterinarian treated the cat with metyrapone, a medication that helps lower cortisol levels. Over time, the cat's skin improved significantly, with the wounds healing and the fur regrowing. Metyrapone was given orally every 12 hours and showed promising results in managing this condition alongside potential surgery.
People also search for: cat skin wounds treatment · hyperadrenocorticism in cats · metyrapone for cats · cat alopecia causes · cat thinning fur treatment
Abstract
Metyrapone, a drug that inhibits cortisol production, was used to lower plasma cortisol concentration and alleviate skin lesions caused by pituitary-dependent hyper-adrenocorticism in a cat. Plasma cortisol concentration was documented by ACTH stimulation test results. During metyrapone treatment, alopecia, thin skin, and large cutaneous wounds resolved. Metyrapone was administered orally at a dosage of 65 mg/kg of body weight, every 12 hours. Metyrapone may be used in conjunction with surgery in the management of pituitary-dependent hyperadrenocorticism in cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8468223/