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Peer-reviewed veterinary case report

How molecular biology helps in pet health and disease

By Zadoks, Ruth N & Schukken, Ynte HΒ·Published in The Veterinary clinics of North America. Food animal practiceΒ·2006Β·College of Veterinary Medicine, United StatesΒ·View original on PubMed β†’

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Original publication title: Use of molecular epidemiology in veterinary practice.

Plain-English summary

Molecular epidemiology is a new area of study that combines molecular biology with the investigation of health and disease in groups of animals. This article explains the terms and methods used in this field and discusses how it can help with large animal medicine and public health for pets and livestock. It looks at how this approach can track disease sources, study vaccines, and understand how infections spread and adapt to different hosts. The examples provided cover a wide range of diseases and species, showing its relevance from global issues down to individual animals. Overall, this research highlights the potential benefits of using molecular techniques in veterinary practice.

Abstract

Molecular epidemiology is a relatively new branch of epidemiology that uses molecular biology methods to study health and disease in populations. This article gives an introduction to molecular epidemiologic terminology and methodology and its usefulness in large animal medicine and veterinary public health. Applications in source tracing and vaccine studies and insights into transmission dynamics, host specificity, and niche adaptation of infectious organisms are presented. Examples are drawn from a variety of diseases, organisms, and host species and range from the global level to the individual-animal level.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16517304/