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Peer-reviewed veterinary case report

Proligestone treatment in German shepherds with pituitary dwarfism

By Knottenbelt, C M & Herrtage, M E·Published in The Journal of small animal practice·2002·Department of Veterinary Clinical Studies, United Kingdom·View original on PubMed

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Original publication title: Use of proligestone in the management of three German shepherd dogs with pituitary dwarfism.

Species:
dog

Plain-English summary

Three German shepherd dogs were diagnosed with pituitary dwarfism, a condition that affects growth and development. They were treated with a medication called proligestone, which helped them develop a proper adult coat, gain weight, and improve their hormone levels. However, two of the dogs experienced side effects, including a serious condition affecting the uterus and abnormal growth, while the third dog had no side effects. Overall, proligestone showed promise in helping these dogs, but pet owners should be aware of potential risks.

People also search for: German shepherd pituitary dwarfism treatment · proligestone side effects in dogs · dog growth hormone therapy

Abstract

Three German shepherd dogs were diagnosed with pituitary dwarfism and subsequently treated with proligestone. Treatment resulted in development of an adult hair coat, increased bodyweight and elevated insulin-like growth factor-1 concentration. Two dogs received thyroid supplementation during proligestone therapy. Adverse effects (cystic endometrial hyperplasia and acromegaly) were reported in two cases. No side effects were reported in the remaining case. This is the first report of the use of proligestone in the management of pituitary dwarfism.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11996393/