Peer-reviewed veterinary case report
Tetrasodium EDTA treatment for blocked ureter devices in cats
By Duval, Valerie et al.·Published in Journal of feline medicine and surgery·2022·Department of Clinical Sciences, Canada·View original on PubMed →
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Original publication title: Use of tetrasodium EDTA acid for the treatment of intraluminal obstruction of subcutaneous ureteral bypass devices.
- Species:
- cat
Plain-English summary
A group of 14 cats with blocked subcutaneous ureteral bypass (SUB) devices underwent a treatment using a 4% tetrasodium EDTA infusion to clear the blockage. The treatment worked for about 69% of the devices, but more than half of those experienced a blockage again within about three months. Some cats had mild side effects like frequent urination or blood in their urine after the treatment, but these issues were temporary. Overall, while the infusion helped many cats, the problem of blockage returned often, indicating that further research is needed to improve treatment options.
People also search for: cat blocked ureter treatment · tetrasodium EDTA for cats · cat urinary blockage symptoms
Abstract
OBJECTIVES: The aim of this study was to evaluate the efficacy and tolerability of a 4% tetrasodium EDTA (tEDTA) infusion protocol in the subcutaneous ureteral bypass (SUB) devices of cats with intraluminal obstruction at a veterinary teaching hospital between July 2017 and April 2020. METHODS: This was a retrospective controlled study. Cats with an obstructed SUB device underwent a 4% tEDTA infusion protocol. Obstruction of the device was diagnosed based on renal pelvic dilation, dilatation of the ureter, mineralized material within the device (cystostomy or nephrostomy catheters) seen on ultrasound, the absence of visible bubbles within the renal pelvis and/or urinary bladder following ultrasound-guided flushing of the device with saline. RESULTS: A total of 16 tEDTA infusion protocols were performed in 14 cats. The infusion protocol was considered successful in 11/16 SUB devices (68.8%). Six devices (n = 6/11; 54.5%) had recurrence of obstruction with a median time of 87 days. One or more episodes of self-limiting pollakiuria and/or hematuria following infusion was seen in eight patients (n = 8/14; 57.1%). CONCLUSIONS AND RELEVANCE: Infusions of 4% tEDTA successfully relieved intraluminal obstruction in patients with occluded SUB devices; however, the recurrence of obstruction was common. Additional studies evaluating case selection and optimal protocols are warranted.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35762269/