Peer-reviewed veterinary case report
Early hip bone changes predict arthritis in Labrador Retrievers
By Powers, Michelle Y et al.·Published in Journal of the American Veterinary Medical Association·2004·Department of Clinical Studies, United States·View original on PubMed →
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Original publication title: Use of the caudolateral curvilinear osteophyte as an early marker for future development of osteoarthritis associated with hip dysplasia in dogs.
- Species:
- dog
Plain-English summary
A group of 48 Labrador Retrievers was studied to see if a specific bone growth called a caudolateral curvilinear osteophyte (CCO) could predict the development of arthritis in their hips. The researchers found that dogs with a CCO were much more likely to show signs of arthritis as they aged, especially those that were not on a restricted diet. In fact, nearly all the dogs with a CCO developed arthritis, while over half of those with a CCO on a restricted diet did as well. This suggests that noticing a CCO early on can help veterinarians identify dogs at risk for hip arthritis later in life.
People also search for: Labrador Retriever hip dysplasia symptoms · dog arthritis treatment · caudolateral curvilinear osteophyte in dogs · signs of hip problems in dogs
Abstract
OBJECTIVE: To determine the relationship between the caudolateral curvilinear osteophyte (CCO) and osteoarthritis associated with hip dysplasia in dogs. DESIGN: Longitudinal cohort study. ANIMALS: 48 Labrador Retrievers from 7 litters. PROCEDURE: In each of 24 sex- and size-matched pairs fed the same diet, a restricted-fed dog was fed 25% less than a control dog for life. The dogs' hips were evaluated in the standard ventrodorsal hip-extended radiographic projection at 16, 30, and 52 weeks of age and then yearly for life. Histologic examination of hip joint tissues was performed on 45 dogs. RESULTS: Median age at death was 11.2 years. Adjusting for feeding group, dogs with a CCO were 3.7 times as likely to develop radiographic signs of osteoarthritis than those without a CCO. Stratified by diet, 100% of the control dogs with a CCO developed radiographic signs of osteoarthritis and 55% of restricted-fed dogs with a CCO developed radiographic signs of osteoarthritis. The CCO was the first radiographic change seen in 22 of 29 (76%) dogs with osteoarthritis. Overall, 35 of 37 (95%) dogs with a CCO had histopathologic lesions of osteoarthritis. CONCLUSIONS AND CLINICAL RELEVANCE: Results indicate a relationship between a CCO on the femoral neck and subsequent development of radiographic signs of osteoarthritis in Labrador Retrievers evaluated over their life span. A CCO is an important early radiographic indication of osteoarthritis associated with canine hip dysplasia.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15323379/