Peer-reviewed veterinary case report
Tissue plasminogen activator clears ureteral bypass clots in cats
By Dropkin, Casey A et al.·Published in Journal of feline medicine and surgery·2021·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Use of tissue plasminogen activator to alleviate postoperative subcutaneous ureteral bypass obstruction secondary to blood clot in seven cats.
- Species:
- cat
Plain-English summary
Seven cats developed a blockage in their urinary bypass system after surgery due to blood clots, which led to increased kidney levels that were detected through imaging. To treat this, a medication called alteplase was used to dissolve the clots, administered either through the bypass port or directly into the bladder. Within two days, all cats had their urinary systems cleared and functioning normally again, with no complications from the treatment.
People also search for: cat urinary blockage treatment · blood clot in cat after surgery · alteplase for cat urinary issues
Abstract
CASE SERIES SUMMARY: Seven cats were found to have postoperative subcutaneous ureteral bypass (SUB) occlusion secondary to blood clot formation. An increase in serum creatinine led to imaging and clot detection in all but one case. Alteplase, a tissue plasminogen activator, was infused into the SUB via the port in four cats, intravesicularly via a transurethral urinary catheter in one cat, and by both routes in two cats. Patency of the SUB was re-established in all cats within 2 days. No short- or long-term complications directly attributed to alteplase administration were observed. RELEVANCE AND NOVEL INFORMATION: The results of this case series suggest that alteplase infusion via either the SUB port and/or a transurethral catheter should be considered prior to surgical intervention for the treatment of postoperative SUB occlusion secondary to a blood clot.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33541238/