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Peer-reviewed veterinary case report

Uterine adenocarcinoma in a Przewalski's wild horse (Equus ferus przewalskii).

Journal:
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians
Year:
2014
Authors:
Thompson, Rachel et al.
Species:
horse

Plain-English summary

A 25-year-old female Przewalski's wild horse, who had a history of a hormonal disorder affecting her pituitary gland, was very tired and eating less than usual. She developed a discharge from her vagina that was both clear and bloody, which led to her being euthanized. A thorough examination after her passing revealed that she had an infiltrative uterine adenocarcinoma, a type of cancer that is rare in horses. This condition is particularly concerning because Przewalski's wild horses are an endangered species, and their reproductive health is crucial for conservation efforts. Unfortunately, the treatment options were not effective in saving her.

Abstract

A 25-yr-old, nulliparous, female Przewalski's wild horse (Equus ferus przewalskii) with a history of pituitary pars intermedia dysfunction and recent onset of serosanguinous vaginal discharge was euthanized after a period of lethargy and inappetance. Postmortem examination confirmed an infiltrative uterine adenocarcinoma, which is an uncommon neoplasia in equids. Reproductive disease is significant in this species as they are considered endangered by IUCN. Reproductive soundness and success are paramount to conservation efforts.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/25000717/