Peer-reviewed veterinary case report
Feline leukemia vaccine effects and long-term cat survival
By Hofmann-Lehmann, Regina et al.·Published in Vaccine·2007·Vetsuisse Faculty·View original on PubMed →
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Original publication title: Vaccination against the feline leukaemia virus: outcome and response categories and long-term follow-up.
- Species:
- cat
Plain-English summary
A study found that while vaccines for feline leukemia virus (FeLV) don't completely stop the virus from integrating into a cat's system, they still protect cats from getting sick and can help them live longer. All cats in the study initially had similar levels of the virus, but how their bodies responded varied, affecting their health outcomes. The researchers used advanced tests to track the virus in the blood, which helped them understand how the infection behaves over time. Overall, vaccination remains an important way to keep cats safe from serious FeLV-related illnesses.
People also search for: cat leukemia vaccine effectiveness · feline leukemia virus symptoms · how long do cats live with FeLV
Abstract
Feline leukaemia virus (FeLV) is a pathogen inducing fatal disease in cats worldwide. By applying sensitive molecular assays, efficacious commonly used FeLV vaccines that protect cats from antigenaemia were found not to prevent proviral integration and minimal viral replication after challenge. Nonetheless, vaccines protected cats from FeLV-associated disease and prolonged life expectancy. The spectrum of host response categories was refined by investigating plasma viral RNA loads. All cats initially fought similar virus loads, although subsequently loads were associated with infection outcomes. Persistence of plasma viral RNA was moderately associated with reactivation of FeLV infection. In conclusion, sensitive molecular assays are important tools for reviewing pathogenesis of FeLV infection.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17240486/