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Peer-reviewed veterinary case report

No link found between recent vaccination and ill-health in dogs

By Edwards, D S et al.·Published in Vaccine·2004·Animal Health Trust, United Kingdom·View original on PubMed

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Original publication title: Vaccination and ill-health in dogs: a lack of temporal association and evidence of equivalence.

Species:
dog

Plain-English summary

A study involving over 4,000 dog owners found no link between recent vaccinations and health problems in dogs. In fact, the results suggested that getting vaccinated might actually lower the chances of health issues by up to 5%. This means that concerns about vaccines causing illness in dogs may not be supported by evidence. Pet owners can feel more confident that vaccinations are safe and beneficial for their dogs' health.

People also search for: dog vaccination side effects · are dog vaccines safe · dog health after vaccination

Abstract

Following concerns raised over the safety of canine vaccines, an epidemiological investigation was conducted to evaluate the evidence for a temporal association between vaccination and ill-health in dogs. The owners of a randomly selected population of dogs were sent 9055 postal questionnaires, 4040 of which were returned. No temporal association was found between vaccination and ill-health in dogs after adjusting for potential confounders, such as age. However, reliable inferences from non-significant test results are limited and so equivalence-testing methods were also used to make informative inferences. Results demonstrated that recent vaccination (< 3 months) does not increase signs of ill-health by more than 0.5% and may actually decrease it by as much as 5%. This general approach should be used in all field studies of vaccine safety.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15308349/