Peer-reviewed veterinary case report
Springer Spaniel died from vaccine shock with heart disease
By Bertola, Luca et al.·Published in Journal of comparative pathology·2022·Department of Veterinary Medicine and Animal Sciences, Italy·View original on PubMed →
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Original publication title: Vaccine-Associated Anaphylactic Shock in a Springer Spaniel Dog with Arrhythmogenic Right Ventricular Cardiomyopathy.
- Species:
- dog
Plain-English summary
A 5-year-old female Springer Spaniel suddenly died after receiving a vaccine for Leptospira. A necropsy revealed severe heart issues and damage to her organs, which were consistent with an allergic reaction to the vaccine, known as anaphylactic shock. This dog also had a rare heart condition called arrhythmogenic right ventricular cardiomyopathy (ARVC), which is more common in Boxer dogs. Unfortunately, the combination of the vaccine and her underlying heart condition led to her tragic death.
People also search for: dog sudden death after vaccination · Springer Spaniel vaccine reaction · arrhythmogenic right ventricular cardiomyopathy in dogs
Abstract
A 5-year-old female Springer Spaniel dog was submitted for necropsy after sudden death following vaccination against Leptospira spp. Gross examination revealed a diffuse dark red discolouration of skeletal musculature, severe diffuse congestion of all the abdominal organs and a contracted spleen. Severe dilation and reduction in wall width was seen in the right ventricle and histological examination revealed multifocal replacement of the right ventricular myocardium by a large amount of fibrofatty tissue. Pathological changes were consistent with post-vaccinal anaphylactic shock in a dog with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare condition typical of Boxer dogs but not previously reported in Springer Spaniels. Canine vaccine-associated adverse events are discussed and ARVC is compared with the corresponding human cardiac condition.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35577457/