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Peer-reviewed veterinary case report

Vaginal discharge in a spayed dog with multiple distinct malignancies.

Journal:
Australian veterinary journal
Year:
2013
Authors:
Christensen, N I et al.
Affiliation:
Small Animal Specialist Hospital · United Kingdom
Species:
dog

Plain-English summary

An 11-year-old female spayed Labrador Retriever was brought to the vet because she was showing signs of heat and had vaginal bleeding, even though she had been spayed at a young age and had never gone into heat before. After thorough testing, the vets found that she had an ovarian granulosa cell tumor, which is a type of tumor that can develop in the ovaries. She also had a history of two other serious tumors: a mast cell tumor five years earlier and a liver tumor eight months before this diagnosis. Both of those previous tumors were treated successfully with surgery and chemotherapy, and at the time of her recent evaluation, there were no signs that the cancer had spread or come back.

Abstract

BACKGROUND: An 11-year-old female spayed Labrador Retriever was presented with clinical signs of oestrus and vaginal bleeding. Historically, the dog had not cycled and had been spayed at less than 6 months of age. RESULTS: Extensive investigation culminated in the diagnosis of an ovarian granulosa cell tumour. The patient had a history of localised grade III mast cell tumour 5 years prior and hepatic haemangiosarcoma 8 months prior to diagnosis. CONCLUSIONS: Both conditions were successfully treated with a combination of surgery and chemotherapy and there was no evidence of metastasis or recurrence at the time of evaluation for signs of oestrus.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23782022/