Peer-reviewed veterinary case report
How vets measure atopic dermatitis severity in dogs
By Olivry, Thierry et al.·Published in Veterinary Dermatology·2007·View original on Crossref →
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Original publication title: Validation of CADESI‐03, a severity scale for clinical trials enrolling dogs with atopic dermatitis
- Species:
- dog
Plain-English summary
A group of 38 dogs with atopic dermatitis (a common allergic skin condition) was evaluated using a new scoring system called CADESI-03 to measure the severity of their skin problems. This updated scale includes more body areas and better reflects symptoms like itching and hair loss. The researchers found that CADESI-03 was reliable and sensitive enough to track changes in the dogs' conditions over time. This means that veterinarians can use this tool to more accurately assess how well treatments are working for dogs with atopic dermatitis.
People also search for: dog itching treatment · atopic dermatitis in dogs · CADESI-03 for dog skin problems
Abstract
AbstractIn dogs, atopic dermatitis (AD) is a common and chronic allergic skin disease that often necessitates treatment with pharmacological interventions. In the last 30 years, numerous clinical trials testing the efficacy of anti‐inflammatory drugs have been reported, but there has been a lack of consistency in the assessment of outcome measures. Several clinical scales have been employed over time, but none of these scoring systems were ever tested for validity and reliability. A committee of the International Task Force on Canine Atopic Dermatitis evaluated the currently available scales used to assess disease morbidity in humans and dogs with AD, and a third version of the Canine Atopic Dermatitis Extent and Severity Index (CADESI‐03) was designed. This version was expanded from previous ones by redistribution and increase in body sites tested, the use of an additional lesion reflecting underlying pruritus (e.g. self‐induced alopecia) and an increase in the numerical range of severity for each lesion. The CADESI‐03 scale was tested for validity and reliability in a cohort of 38 dogs with AD. Overall, this revised version of the CADESI was found to exhibit acceptable content, construct, criterion, and inter‐ and intra‐observer reliability and sensitivity to change. As a result, this scale is recommended as a validated tool for assessment of disease severity in clinical trials testing the efficacy of interventions in dogs with AD.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/j.1365-3164.2007.00569.x