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Peer-reviewed veterinary case report

Validation of Coronary Wire for the Acquisition of Intracoronary Electrocardiogram in Swine.

Journal:
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Year:
2025
Authors:
Vassilev, Dobrin Iotkov et al.
Affiliation:
SHATC "Medica Cor"

Abstract

BACKGROUND: We report the first in-literature animal experiment to validate the intracoronary ECG signal acquired from a coronary wire compared with the direct signal from an epicardial electrode. METHODS: An animal model study was performed in a 40 kg pig. Acute myocardial ischemia was induced by intracoronary balloon inflation for 60 s. Simultaneous ECG recording and PCI guidewire electrical and motion measurements were obtained. RESULTS: The first ischemic manifestation was myocardial kinetic disturbances, followed by ST-elevation. The signals recorded from the PCI guidewire and the epicardial electrode ran simultaneously, from the induction of ischemia to complete recovery of signal. CONCLUSION: The intracoronary ECG signal acquired from a coronary wire was equivalent to the direct signal received from an epicardial electrode. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT04061525.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/40916341/