Peer-reviewed veterinary case report
DNA test for hip dysplasia not reliable in Danish Labradors
By Bruun, C S et al.·Published in Animal genetics·2020·Department of Veterinary and Animal Sciences·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Validation of DNA test for hip dysplasia failed in Danish Labrador Retrievers.
- Species:
- dog
Plain-English summary
A group of 39 Danish Labrador Retrievers was tested for hip dysplasia using a genetic test called the Dysgen test, which was developed based on findings from Spanish Labradors. The dogs included 14 with hip dysplasia and 25 without. However, the results showed no significant link between the test outcomes and the actual hip health of the dogs, meaning the Dysgen test isn't reliable for predicting hip dysplasia in this breed. Pet owners should be aware that this genetic test may not be useful for assessing their dog's hip health.
People also search for: dog hip dysplasia test · Labrador Retriever hip problems · how to check for hip dysplasia in dogs
Abstract
Canine hip dysplasia is characterized by poor hip joint conformation and laxity. The disease is a complex trait influenced by both genetics and environment. Diagnosis and quantification of hip dysplasia are performed by radiographic examination of the hip joint and the diagnosis is used for making breeding decisions in many breeds. A prognostic genetic test (the Dysgen test) based on seven associated SNPs has been developed in a study based on Spanish Labrador Retrievers. In our study this test has been evaluated in 39 Danish Labrador Retrievers with known radiographic hip score: 14 with hip dysplasia (grade D or E) and 25 without hip dysplasia (grade A or B). There was no significant correlation between the Dysgen test results and the radiographic hip status (P = 0.3203) in these dogs, indicating that Dysgen test results obtained for Danish Labrador Retrievers have no prognostic value.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32432791/