Peer-reviewed veterinary case report
Vedaprofen reduces fever in cats with respiratory infection
By Lopez, S et al.·Published in The Journal of small animal practice·2007·Intervet Pharma R&D, France·View original on PubMed →
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Original publication title: Vedaprofen therapy in cats with upper respiratory tract infection or following ovariohysterectomy.
- Species:
- cat
Plain-English summary
A group of cats with upper respiratory infections were treated with vedaprofen, a medication that helps reduce fever and pain. The cats that received vedaprofen showed a significant drop in body temperature and were more likely to feel better within a week compared to those who only received antibiotics. In another group of cats that had just undergone spay surgery, those treated with vedaprofen also recovered faster and had better behavior and appetite in the days following the procedure. Overall, vedaprofen proved to be effective in helping cats feel more comfortable and recover more quickly from both infections and surgery.
People also search for: cat upper respiratory infection treatment · vedaprofen for cats · cat spay recovery tips
Abstract
OBJECTIVES: The antipyretic and analgesic efficacy of vedaprofen (at a dose of 0.5 mg/kg) was evaluated after repeated once-daily administration (for three or five days) to 80 cats with upper respiratory tract disease or 302 cats undergoing ovariohysterectomy. METHODS: Both clinical trials were randomised, double blinded and placebo controlled. RESULTS: In the upper respiratory tract disease trial, vedaprofen produced a significant reduction in rectal temperature when compared with cats administered antimicrobial treatment only. This antipyretic activity lasted at least four hours after administration on the first day of treatment (day 0) and at least eight hours on day 1 and day 2. Significantly more cats in the treatment group were classified as having returned to normal on day 5, day 6 and day 7 compared with the placebo group. In the ovariohysterectomy trial, scores for behaviour (on day 1, day 2 and day 3) and appetite (on day 1 and day 2) were significantly better in the vedaprofen group than in the placebo-treated cats. CLINICAL SIGNIFICANCE: Vedaprofen produced a clinically relevant reduction in body temperature and a more rapid return to normality in cats with upper respiratory tract disease. Vedaprofen treatment also resulted in more rapid recovery, presumably through the relief of pain and inflammation, in cats that had undergone soft tissue surgery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17286658/