Peer-reviewed veterinary case report
Ventriculomegaly and brain changes in Cavalier King Charles Spaniels
By Tirrito, Federica et al.·Published in The Journal of veterinary medical science·2022·Clinica Neurologica Veterinaria NVA, Italy·View original on PubMed →
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Original publication title: Ventriculomegaly in Cavalier King Charles Spaniels with Chiari-like malformation: relationship with clinical and imaging findings.
- Species:
- dog
Plain-English summary
A group of Cavalier King Charles Spaniels with Chiari-like malformation (a brain condition) showed that 70% had enlarged brain ventricles (ventriculomegaly). The most common symptoms noticed by owners included scratching and neck pain, and 28% of the dogs experienced seizures. Despite the high prevalence of ventriculomegaly, researchers found no clear link between the size of the ventricles and the severity of symptoms or other imaging findings. This suggests that while many affected dogs have enlarged ventricles, it doesn't necessarily correlate with how severe their condition is or whether they have seizures.
People also search for: Cavalier King Charles Spaniel scratching neck pain · Chiari-like malformation in dogs · dog seizures treatment · ventriculomegaly in dogs · dog brain condition symptoms
Abstract
The objective of this study was to calculate lateral ventricles dimension in Cavalier King Charles Spaniel dogs with Chiari-like malformation and investigate the association between ventriculomegaly and signalment, clinical signs, ventricular asymmetry, grade of Chiari-like malformation, syringomyelia and index of medullary kinking. Retrospectively, 43 client-owned Cavalier King Charles Spaniels, older than 1 year of age, with magnetic resonance imaging diagnosis of Chiari-like malformation were enrolled. Initial and follow-up (up to 36 months) clinical status was graded. Images were reviewed to quantify the enlargement of lateral ventricles, evaluate ventricular symmetry, grade of Chiari-like malformation, grade of syringomyelia and medullary kinking index. Cases presenting epileptic seizures during the evaluation period were also recorded. The most common initial clinical signs were scratching and neck pain. Ventriculomegaly was identified in 70% of dogs, Chiari-like malformation grade 2 was observed in 77% of cases, ventricular asymmetry and syringomyelia were identified in 54% and 80% of dogs, respectively; the median medullary kinking index was 37.77%. Moreover, 28% of dogs presented epileptic seizures. No significant association was identified between dimension of lateral ventricles and signalment, clinical signs, and imaging findings; no significant association was identified between ventriculomegaly and epilepsy (P≥0.05). In conclusion, the prevalence of ventriculomegaly in Cavalier King Charles Spaniels is high but this finding does not seem related to the severity of clinical signs, presence of Chiari-like malformation, syringomyelia and craniocervical junction abnormalities such as medullary kinking.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35831130/